Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Obesity remains the most important risk factor for the incidence and progression of
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …

Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

Intervertebral disc degeneration (IDD) and osteoarthritis (OA) affecting the facet joint of the
spine are biomechanically interdependent, typically occur in tandem, and have considerable …

Osteoarthritis is a debilitating chronic disease that manifests with widely varying
symptomatology. Inflammation is now appreciated as a key pathophysiological process in …

Synovial joints are complex structures that enable normal locomotion. Following injury, they
undergo a series of changes, including a prevalent inflammatory response. This increases …

Objective Obesity was once considered a risk factor for knee osteoarthritis (OA) primarily for
biomechanical reasons. Here we provide an additional perspective by discussing how …

Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people world-
wide. Accumulating evidence attests to the important roles of the immune system in OA …

Osteoarthritis (OA) is a joint disease featuring cartilage breakdown and chronic pain.
Although age and joint trauma are prominently associated with OA occurrence, the trigger …