Anti-MDA5 dermatomyositis is a rare systemic autoimmune disease, historically described in
Japanese patients with clinically amyopathic dermatomyositis and life-threatening rapidly …

Dermatomyositis (DM) is an idiopathic inflammatory myopathy that is clinically
heterogeneous and that can be difficult to diagnose. Cutaneous manifestations sometimes …

Anti-melanoma differentiation-associated gene 5–positive dermatomyositis (MDA5+ DM) is
a rare autoimmune disease predominantly reported in East Asia. MDA5+ DM is an …

The idiopathic inflammatory myopathies are characterized by muscle weakness, skin
disease and internal organ involvement. Autoimmunity is known to have a role in myositis …

Objectives The predominance of extramuscular manifestations (eg, skin rash, arthralgia,
interstitial lung disease [ILD]) as well as the low frequency of muscle signs in anti …

Autoantibodies specific for idiopathic inflammatory myopathy (myositis-specific
autoantibodies (MSAs)) are clinically useful biomarkers to help the diagnosis of …

Idiopathic inflammatory myopathies (IIM) are a heterogenous family of diseases that can
affect the muscles, skin, lungs, and joints. There have been prior attempts to classify IIMs …

The discovery of novel autoantigen systems related to idiopathic inflammatory myopathies
(collectively referred to as myositis) in adults and children has had major implications for the …

The lung is a common site of complications of systemic connective tissue disease (CTD),
and lung involvement can present in several ways. Interstitial lung disease (ILD) and …

Objective Since dermatomyositis (DM) is associated with an increased risk of malignancy,
accurate identification of patients likely to harbor cancers is important. Using …