Berberine is a natural pentacyclic isoquinoline alkaloid that has been isolated as the
principal component of many popular medicinal plants such as the genus Berberis, Coptis …

Sepsis and septic shock are characterized by life-threatening organ dysfunction caused by a
dysregulated host response to infection. The liver has a central role during sepsis, and is …

The gut microbiota drives individual sensitivity to excess acetaminophen (APAP)-mediated
hepatotoxicity. It has been reported that the bacterium Akkermansia muciniphila protects …

Inflammation and hepatocyte injury and death are the hallmarks of nonalcoholic
steatohepatitis (NASH), the progressive form of nonalcoholic fatty liver disease (NAFLD) …

The digestive tract is replete with complex and diverse microbial communities that are
important for the regulation of multiple pathophysiological processes in humans and …

The polysaccharides from Auricularia auricula (AAPs), containing a large number of O-acetyl
groups that are related to the physiological and biological properties, seem to be potential …

The liver is a unique organ with an abundant regenerative capacity. Therefore, partial
hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver …

There is increasing evidence for the role of gut microbial composition in the pathogenesis of
nonalcoholic fatty liver disease (NAFLD). Nonalcoholic steatohepatitis (NASH) is the most …

Farnesoid X receptor (FXR), a metabolic nuclear receptor, plays critical roles in the
maintenance of systemic energy homeostasis and the integrity of many organs, including …

Autoimmune cholestatic liver diseases, including primary biliary cholangitis (PBC) and
primary sclerosing cholangitis (PSC), are manifested as an impairment of normal bile flow …