[HTML][HTML] Essential oils as multicomponent mixtures and their potential for human health and well-being

M Bunse, R Daniels, C Gründemann… - Frontiers in …, 2022 - frontiersin.org
Essential oils (EOs) and their individual volatile organic constituents have been an inherent
part of our civilization for thousands of years. They are widely used as fragrances in …

Administration of resveratrol: what formulation solutions to bioavailability limitations?

A Amri, JC Chaumeil, S Sfar, C Charrueau - Journal of controlled release, 2012 - Elsevier
Resveratrol (3, 5, 4′-trihydroxystilbene), a naturally occurring polyphenol, has attracted
considerable interest for its beneficial potentials for human health, which include anti …

The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability

DJ McClements, F Li, H Xiao - Annual review of food science …, 2015 - annualreviews.org
The oral bioavailability of a health-promoting dietary component (nutraceutical) may be
limited by various physicochemical and physiological phenomena: liberation from food …

In vivo methods for drug absorption–comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API …

E Sjögren, B Abrahamsson, P Augustijns… - European Journal of …, 2014 - Elsevier
This review summarizes the current knowledge on anatomy and physiology of the human
gastrointestinal tract in comparison with that of common laboratory animals (dog, pig, rat and …

[HTML][HTML] Predicting oral drug absorption: mini review on physiologically-based pharmacokinetic models

L Lin, H Wong - Pharmaceutics, 2017 - mdpi.com
Most marketed drugs are administered orally, despite the complex process of oral
absorption that is difficult to predict. Oral bioavailability is dependent on the interplay …

Animal farm: considerations in animal gastrointestinal physiology and relevance to drug delivery in humans

GB Hatton, V Yadav, AW Basit, HA Merchant - Journal of pharmaceutical …, 2015 - Elsevier
ABSTRACT" All animals are equal, but some are more equal than others" was the illustrious
quote derived from British writer George Orwell's famed work, Animal Farm. Extending …

Navigating the human gastrointestinal tract for oral drug delivery: Uncharted waters and new frontiers

M Koziolek, M Grimm, F Schneider, P Jedamzik… - Advanced Drug Delivery …, 2016 - Elsevier
Many concepts of oral drug delivery are based on our comprehension of human
gastrointestinal physiology. Unfortunately, we tend to oversimplify the complex interplay …

Excipient foods: designing food matrices that improve the oral bioavailability of pharmaceuticals and nutraceuticals

DJ McClements, H Xiao - Food & Function, 2014 - pubs.rsc.org
The oral bioavailability of many lipophilic bioactive agents (pharmaceuticals and
nutraceuticals) is limited due to various physicochemical and physiological processes: poor …

[HTML][HTML] Echinacoside: a promising active natural products and pharmacological agents

W Wang, S Jiang, Y Zhao, G Zhu - Pharmacological Research, 2023 - Elsevier
Echinacoside, a natural phenylethanoid glycoside, was discovered and isolated from the
garden plant Echinacea angustifolia DC., belonging to the Compositae family …

Enhancing nutraceutical performance using excipient foods: Designing food structures and compositions to increase bioavailability

DJ McClements, L Zou, R Zhang… - … Reviews in Food …, 2015 - Wiley Online Library
The oral bioavailability of many bioactives (pharmaceuticals, dietary supplements, nutrients,
and nutraceuticals) is limited because of physicochemical and physiological events that …