Surgical intensive care unit (ICU) stay of longer than 10 days is often described by the
experienced intensivist as a “complicated clinical course” and is frequently attributed to …

Multiple organ failure (MOF) has plagued surgical intensive care units (ICUs) for more than
four decades, and its epidemiology has evolved because advances in care have allowed …

Objective Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS)
have been increasingly recognized in the critically ill over the past decade. The variety of …

Background Damage control surgery is a management sequence initiated to reduce the risk
of death in severely injured patients presenting with physiological derangement. Damage …

Abdominal compartment syndrome (ACS) is the end point of a process whereby massive
interstitial swelling in the abdomen or rapid development of a space-filling lesion in the …

As advances in prehospital and acute hospital care conquered the so-called golden hour,
multiple organ failure (MOF) emerged as the leading cause of late trauma death. 1–3 …

Objective: The objective of this study was to determine the epidemiology and outcomes of
intra-abdominal hypertension in a heterogeneous intensive care unit population. Design …

In the late 1980s, the Denver Multiple Organ Failure (MOF) database was developed to
prospectively characterize postinjury MOF. At this time, MOF was a frequent, poorly …

Postinjury multiple organ failure (MOF) became prevalent as the improvements in critical
care during the 1970s made it possible to keep trauma patients alive with single organ …

Despite the enormous efforts to elucidate the mechanisms of the development of multiple
organ failure (MOF) following trauma, MOF following trauma is still a leading cause of late …