Vegetable biomass is generated from CO2 and H2O using sunlight as the energy source,
producing O2 as a subproduct. The primary products formed are C6-and C5-sugars that …

Metal-catalyzed reactions have made a great contribution to the recent growth of organic
synthesis, and a variety of synthetic methods have been reported using mainly group 8 …

Aromatic ring isosteres and rigidified saturated hydrocarbons are important motifs to enable
drug discovery. Herein we disclose [2]-ladderanes as a class of meta-substituted aromatic …

Bicyclo [2.1. 1] hexanes have become increasingly popular building blocks in medicinal
chemistry as bridged scaffolds that provide unexplored chemical space. We herein report a …

With the postgenome era rapidly approaching, new strategies for the functional analysis of
proteins are needed. To date, proteomics efforts have primarily been confined to recording …

C-3 hydroxyl protection (TCE-C1), acetylation, and deprotection (Zn/HOAc, then H2, Pd/C).
The overall yield from the syn epoxide was an impressive 75%. Pyrrole itself, as in the case …

Biomass is renewable and the most abundant carbon resource, and it shows great potential
for sustainable production of chemicals in the future. With respect to limited fossil reserves …

This article reviews the oxidations of a wide range of molecules with tetrapropylammonium
perruthenate including examples of both double oxidations and selective oxidations …

In this study, we report the first total hemisynthesis of trans-himachalol sesquiterpene, a
stereoisomer of the natural cis-himachalol isolated from Cedrus atlantica essential oils, from …

Since the discovery of penicillin nearly a century ago, βlactam antibiotics have continued to
capture the attention of the synthetic and medicinal chemistry communities. In particular, the …