Generating biopharmaceuticals in genetically engineered bioreactors continues to reign
supreme. Hence, genetically engineered birds have attracted considerable attention from …

We report here the generation of transgenic chickens that produce human granulocyte‐
colony stimulating factor (hG‐CSF) using replication‐defective Moloney murine leukemia …

Background Swine is an important agricultural commodity and biomedical model.
Manipulation of the pig genome provides opportunity to improve production efficiency …

We report the creation of a transgenic dog that conditionally expresses eGFP (enhanced
green fluorescent protein) under the regulation of doxycycline. Briefly, fetal fibroblasts …

A critical problem in the production of transgenic animals is the uncontrolled constitutive
expression of the foreign gene, which occasionally results in serious physiological disorders …

Interspecies somatic cell nuclear transfer (iSCNT) has emerged as an important tool for
studying nucleo‐cytoplasmic interactions and cloning of animals whose oocytes are difficult …

Pigs are anatomically and physiologically closer to humans than other laboratory animals.
Transgenic (TG) pigs are widely used as models of human diseases. The aim of this study …

Transgenic chickens, ubiquitously expressing a human protein, could be a very useful
model system for studying the role of human proteins in embryonic development as well as …

Amino acids play a multitude of roles during early embryonic development and have been
demonstrated to facilitate improved development of in vivo or in vitro fertilized and …

This study investigated the influence of the sexual maturity and reproductive phase of oocyte
donor on the developmental ability and quality of porcine embryos produced by somatic cell …