Epidemiology and treatment of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa infections

JP Horcajada, M Montero, A Oliver, L Sorlí… - Clinical microbiology …, 2019 - Am Soc Microbiol
In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

The Building Blocks of Antimicrobial Resistance in Pseudomonas aeruginosa: Implications for Current Resistance-Breaking Therapies

RF Langendonk, DR Neill, JL Fothergill - Frontiers in Cellular and …, 2021 - frontiersin.org
P. aeruginosa is classified as a priority one pathogen by the World Health Organisation, and
new drugs are urgently needed, due to the emergence of multidrug-resistant (MDR) strains …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

The increasing threat of Pseudomonas aeruginosa high-risk clones

A Oliver, X Mulet, C López-Causapé, C Juan - Drug Resistance Updates, 2015 - Elsevier
The increasing prevalence of chronic and hospital-acquired infections produced by
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …

β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospects

KA Glen, IL Lamont - Pathogens, 2021 - mdpi.com
Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …

Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence

M Sultan, R Arya, KK Kim - International journal of molecular sciences, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Update on infections caused by Stenotrophomonas maltophilia with particular attention to resistance mechanisms and therapeutic options

YT Chang, CY Lin, YH Chen, PR Hsueh - Frontiers in microbiology, 2015 - frontiersin.org
Stenotrophomonas maltophilia is a Gram-negative, biofilm-forming bacterium. Although
generally regarded as an organism of low virulence, S. maltophilia is an emerging multi …

Pseudomonas genomes: diverse and adaptable

MW Silby, C Winstanley, SAC Godfrey… - FEMS microbiology …, 2011 - academic.oup.com
Members of the genus Pseudomonas inhabit a wide variety of environments, which is
reflected in their versatile metabolic capacity and broad potential for adaptation to fluctuating …

Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

PD Lister, DJ Wolter, ND Hanson - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Treatment of infectious diseases becomes more challenging with each passing year. This is
especially true for infections caused by the opportunistic pathogen Pseudomonas …