Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …

Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …

The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

Abstract γδ T cells are important tissue-resident, innate T cells that are critical for tissue
homeostasis. γδ cells are associated with positive prognosis in most tumors; however, little …

Evidence suggests that innate and adaptive cellular responses mediate resistance to the
influenza virus and confer protection after vaccination. However, few studies have resolved …

BACKGROUND In addition to providing antimicrobial immunity, the immune system governs
numerous aspects of host physiology, in part through the coordinated action of tissue …

IL-17A–producing γδ T cells in mice consist primarily of Vγ6+ tissue-resident cells and Vγ4+
circulating cells. How these γδ T cell subsets are regulated during homeostasis and cancer …

Abstract Foxp3+ regulatory T (Treg) cells expressing the interleukin (IL)-33 receptor ST2
mediate tissue repair in response to IL-33. Whether Treg cells also respond to the alarmin IL …

Ketone bodies are essential alternative fuels that allow humans to survive periods of
glucose scarcity induced by starvation and prolonged exercise. A widely used ketogenic diet …