A promising paradigm to regenerative medicine involves the application of biomaterials,
which makes a spurt of progress in the past 20 years. Of various biomaterials, decellularized …

All terrestrial organisms have evolved and adapted to thrive under Earth's gravitational force.
Due to the increase of crewed space flights in recent years, it is vital to understand how the …

Collagen alignment is one of the key microarchitectural signatures of many pathological
conditions, including scarring and fibrosis. Investigating how collagen alignment modulates …

Protein/peptide-based hydrogel biomaterial inks with the ability to incorporate various cells
and mimic the extracellular matrix's function are promising candidates for 3D printing and …

Considering the substantial role played by dendritic cells (DCs) in the immune system to
bridge innate and adaptive immunity, studies on DC-mediated immunity toward biomaterials …

Microgravity accelerates the aging of various physiological systems, and it is well
acknowledged that aged individuals and astronauts both have increased susceptibility to …

The remarkable success of targeted immunotherapies is revolutionizing cancer treatment.
However, tumor heterogeneity and low immunogenicity, in addition to several tumor …

Dendritic cells (DCs), the most potent antigen-presenting cells, are necessary for the
effective activation of naïve T cells. DCs encounter numerous microenvironments with …

Tissue-resident myeloid cells sense and transduce mechanical signals such as stiffness,
stretch and compression. In the past two years, our understanding of the mechanosensitive …

Mechanical forces are pervasive in the inflammatory site where dendritic cells (DCs) are
activated to migrate into draining lymph nodes. For example, fluid shear stress modulates …