Mycotoxins co-contamination: Methodological aspects and biological relevance of combined toxicity studies

I Alassane-Kpembi, G Schatzmayr… - Critical Reviews in …, 2017 - Taylor & Francis
Mycotoxins are secondary fungal metabolites produced mainly by Aspergillus, Penicillium,
and Fusarium. As evidenced by large-scale surveys, humans and animals are …

The intestinal barrier as an emerging target in the toxicological assessment of mycotoxins

P Akbari, S Braber, S Varasteh, A Alizadeh… - Archives of …, 2017 - Springer
Mycotoxins, the secondary metabolites of fungal species, are the most frequently occurring
natural food contaminants in human and animal diets. Risk assessment of mycotoxins …

Genotoxic effects of mycotoxins

TG Ülger, A Uçar, FP Çakıroğlu, S Yilmaz - Toxicon, 2020 - Elsevier
Fungi produce mycotoxins in the presence of appropriate temperature, humidity, sufficient
nutrients and if the density of the mushroom mass is favorable. Although all mycotoxins are …

Toxicological interactions between the mycotoxins deoxynivalenol, nivalenol and their acetylated derivatives in intestinal epithelial cells

I Alassane-Kpembi, O Puel, IP Oswald - Archives of toxicology, 2015 - Springer
In case of mycotoxin contaminations, food and feedstuff are usually contaminated by more
than one toxin. However toxicological data concerning the effects of mycotoxin combinations …

Aflatoxin B1 invokes apoptosis via death receptor pathway in hepatocytes

MJ Mughal, X Peng, Y Zhou, J Fang - Oncotarget, 2016 - pmc.ncbi.nlm.nih.gov
The fungal metabolites produced by Aspergillus flavus and Aspergillus parasiticus cause
detrimental health effects on humans and animals. Particularly aflatoxin B1 (AFB1) is the …

Appropriateness to set a group health‐based guidance value for fumonisins and their modified forms

EFSA Panel on Contaminants in the Food Chain … - Efsa …, 2018 - Wiley Online Library
Abstract The EFSA Panel on Contaminants in the Food Chain (CONTAM) established a
tolerable daily intake (TDI) for fumonisin B1 (FB 1) of 1.0 μg/kg body weight (bw) per day …

Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression

A Fishbein, W Wang, H Yang, J Yang… - Proceedings of the …, 2020 - National Acad Sciences
Toxic environmental carcinogens promote cancer via genotoxic and nongenotoxic
pathways, but nongenetic mechanisms remain poorly characterized. Carcinogen-induced …

[HTML][HTML] Aflatoxin B1 disrupts the intestinal barrier integrity by reducing junction protein and promoting apoptosis in pigs and mice

M Zhang, Q Li, J Wang, J Sun, Y Xiang, X Jin - … and Environmental Safety, 2022 - Elsevier
With the growing diversity and complexity of diet, animals and humans are at risk of
exposure to aflatoxin B1 (AFB1), which is a well-known contaminant in the food chain that …

Aflatoxin M1 cytotoxicity against human intestinal Caco-2 cells is enhanced in the presence of other mycotoxins

YN Gao, JQ Wang, SL Li, YD Zhang, N Zheng - Food and Chemical …, 2016 - Elsevier
Abstract Aflatoxin M1 (AFM1), a class 2B human carcinogen, is the only mycotoxin with
established maximum residue limits (MRLs) in milk. Toxicological data for other mycotoxins …

[HTML][HTML] Effects of feeding corn naturally contaminated with aflatoxin B1 and B2 on hepatic functions of broilers

J Yang, F Bai, K Zhang, S Bai, X Peng, X Ding, Y Li… - Poultry science, 2012 - Elsevier
The purpose of this study was to evaluate the effects of feeding corn naturally contaminated
with aflatoxin B 1 (AFB 1) and aflatoxin B 2 (AFB 2) on serum biochemical parameters …