The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction

AB Cornwell, Y Zhang, M Thondamal, DW Johnson… - GeroScience, 2024 - Springer
Dietary restriction (DR), the process of decreasing overall food consumption over an
extended period of time, has been shown to increase longevity across evolutionarily diverse …

[HTML][HTML] DOT1L stimulates MYC/Mondo transcription factor activity by promoting its degradation cycle on chromatin

GP Sepulveda, ES Gushchanskaia, A Mora-Martin… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The proto-oncogene c-MYC is a key representative of the MYC transcription factor network
regulating growth and metabolism. MML-1 (Myc-and Mondo-like) is its homolog in C …