The melanin-concentrating hormone (MCH) system: a tale of two peptides

GB Diniz, JC Bittencourt - Frontiers in neuroscience, 2019 - frontiersin.org
The melanin-concentrating hormone (MCH) system is a robust integrator of exogenous and
endogenous information, modulating arousal and energy balance in mammals. Its …

Is melanin-concentrating hormone in the medial preoptic area a signal for the decline of maternal care in late postpartum?: MCH in maternal behavior

M Li - Frontiers in Neuroendocrinology, 2024 - Elsevier
This manuscript proposes that melanin-concentrating hormone (MCH) in the medial preoptic
area (MPOA) is an neurochemical signal evolved to trigger the declining process of maternal …

[图书][B] The parental brain: mechanisms, development, and evolution

M Numan - 2020 - books.google.com
The Parental Brain: Mechanisms, Development, and Evolution presents a comprehensive
analysis of how the brain regulates parental behavior in nonhuman animals and in humans …

Regulation of brain primary cilia length by MCH signaling: evidence from pharmacological, genetic, optogenetic, and chemogenic manipulations

W Alhassen, Y Kobayashi, J Su, B Robbins… - Molecular …, 2022 - Springer
The melanin-concentrating hormone (MCH) system is involved in numerous functions,
including energy homeostasis, food intake, sleep, stress, mood, aggression, reward …

Ciliary melanin‐concentrating hormone receptor 1 (MCHR1) is widely distributed in the murine CNS in a sex‐independent manner

GB Diniz, DS Battagello, MO Klein… - Journal of …, 2020 - Wiley Online Library
Melanin‐concentrating hormone (MCH) is a ubiquitous vertebrate neuropeptide
predominantly synthesized by neurons of the diencephalon that can act through two G …

Mating and parenting experiences sculpture mood-modulating effects of oxytocin-MCH signaling

J Phan, L Alhassen, A Argelagos, W Alhassen… - Scientific reports, 2020 - nature.com
The two hypothalamic neuropeptides oxytocin and melanin concentrating hormone (MCH)
share several physiological actions such as the control of maternal care, sexual behavior …

Novel aspect of oxytocin neurons mediating parental behavior and aversive burying behavior under the control of melanin-concentrating hormone neurons

T Xiong, L Tsuchida, A Inutsuka, T Onaka… - Frontiers in Behavioral …, 2024 - frontiersin.org
Parental behavior comprises a set of crucial actions essential for offspring survival. In this
study, a double transgenic mouse model engineered to specifically express …

Loss of glutamatergic signalling from MCH neurons reduced anxiety‐like behaviours in novel environments

AS Sankhe, D Bordeleau, DIM Alfonso… - Journal of …, 2023 - Wiley Online Library
Melanin‐concentrating hormone (MCH) neurons within the hypothalamus are
heterogeneous and can coexpress additional neuropeptides and transmitters. The majority …

Regulation and neurochemical identity of melanin‐concentrating hormone neurones in the preoptic area of lactating mice

PDS Teixeira, F Wasinski, LB Lima… - Journal of …, 2020 - Wiley Online Library
Neurones expressing the melanin‐concentrating hormone (MCH) can be found in the
medial preoptic area (mPOA) and ventral aspects of the periventricular preoptic nucleus of …

Melanin concentrating hormone signaling deficits in schizophrenia: association with memory and social impairments and abnormal sensorimotor gating

MP Vawter, A Schulmann, L Alhassen… - International Journal …, 2020 - academic.oup.com
Background Evidence from anatomical, pharmacological, and genetic studies supports a
role for the neuropeptide melanin concentrating hormone system in modulating emotional …