Neural circuits are assembled with remarkable precision during embryonic development,
and the selectivity inherent in their formation helps to define the behavioural repertoire of the …

The functioning of the nervous system depends upon the underlying detailed and highly
stereotyped patterns of neuronal connectivity. How these precise patterns of synaptic …

The homeobox gene Hb9, like its close relative MNR2, is expressed selectively by motor
neurons (MNs) in the developing vertebrate CNS. In embryonic chick spinal cord, the ectopic …

* Howard Hughes Medical Institute Department of Biochemistry and Molecuiar Biophysics
Center for Neurobiology and Behavior Columbia University New York, New York 10032 …

A prerequisite for many studies of neurons in culture is a means of determining their original
identity. We needed such a technique to study the interactions in vitro between a class of …

Social dilemmas occur when the pursuit of self-interest by individuals in a group leads to
less than optimal collective outcomes for everyone in the group. A critical assumption in the …

Spinal motor neurons acquire specialized" pool" identities that determine their ability to form
selective connections with target muscles in the limb, but the molecular basis of this striking …

▪ Abstract The topographic assembly of neural circuits is dependent upon the generation of
specific neuronal subtypes, each subtype displaying unique properties that direct the …

Motor behaviors are the primary means by which animals interact with their environment,
forming the final output of most central nervous system (CNS) activity. The neural circuits that …

The circuits that control movement are comprised of discrete subtypes of motor neurons.
How motor neuron subclasses develop and extend axons to their correct targets is still …