Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …

Objective In diabetes, vascular dysfunction is characterized by impaired endothelial function
due to increased oxidative stress. Empagliflozin, as a selective sodium-glucose co …

Diabetic cardiomyopathy (DCM), a common consequence of longstanding diabetes mellitus,
is initiated by death of cardiomyocyte. Hyperglycemia-induced reactive oxygen species …

Background and Objectives: This experiment evaluated the preventative influence of the
tomato-derived Esculeoside A (ESA) on diabetic cardiomyopathy in type 1 diabetes mellitus …

The aim of the present study was to determine the role of hydrogen sulfide (H2S) in
improving myocardial fibrosis and its effects on oxidative stress, endoplasmic reticulum (ER) …

Ginsenoside Rg1 has been demonstrated to have cardiovascular protective effects.
However, whether the cardioprotective effects of ginsenoside Rg1 are mediated by …

Oxidative stress is closely associated with the pathophysiology of diabetic cardiomyopathy
(DCM). The mitochondrial flavoenzyme monoamine oxidase A (MAO-A) is an important …

Oxidative stress plays a key role for the development of cardiovascular, metabolic, and
neurodegenerative disease. This concept has been proven by using the approach of genetic …

The present study aimed to investigate the protective effect of sitagliptin, a dipeptidyl
peptidase-4 inhibitor, on diabetic cardiomyopathy (DCM)-associated apoptosis and if this …