International consensus based review and recommendations for minimum reporting standards in research on transcutaneous vagus nerve stimulation (version 2020)

AD Farmer, A Strzelczyk, A Finisguerra… - Frontiers in human …, 2021 - frontiersin.org
Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus
nerve stimulation (tVNS) across basic, translational and clinical research …

Declining locus coeruleus–dopaminergic and noradrenergic modulation of long-term memory in aging and Alzheimer's disease

MJ Dahl, A Kulesza, M Werkle-Bergner… - … & Biobehavioral Reviews, 2023 - Elsevier
Memory is essential in defining our identity by guiding behavior based on past experiences.
However, aging leads to declining memory, disrupting older adult's lives. Memories are …

Gut microbiota changes require vagus nerve integrity to promote depressive-like behaviors in mice

E Siopi, M Galerne, M Rivagorda, S Saha… - Molecular …, 2023 - nature.com
Chronic stress constitutes a major risk factor for depression that can disrupt various aspects
of homeostasis, including the gut microbiome (GM). We have recently shown that GM …

[HTML][HTML] Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement

S Bowles, J Hickman, X Peng, WR Williamson… - Neuron, 2022 - cell.com
Vagus nerve stimulation (VNS) is a neuromodulation therapy for a broad and expanding set
of neurologic conditions. However, the mechanism through which VNS influences central …

Transcutaneous vagus nerve stimulation in humans induces pupil dilation and attenuates alpha oscillations

O Sharon, F Fahoum, Y Nir - Journal of Neuroscience, 2021 - Soc Neuroscience
Vagus nerve stimulation (VNS) is widely used to treat drug-resistant epilepsy and
depression. While the precise mechanisms mediating its long-term therapeutic effects are …

Noradrenergic modulation of rhythmic neural activity shapes selective attention

MJ Dahl, M Mather, M Werkle-Bergner - Trends in cognitive sciences, 2022 - cell.com
During moments involving selective attention, the thalamus orchestrates the preferential
processing of prioritized information by coordinating rhythmic neural activity within a …

Phasic, event-related transcutaneous auricular vagus nerve stimulation modifies behavioral, pupillary, and low-frequency oscillatory power responses

C Wienke, M Grueschow, A Haghikia… - Journal of …, 2023 - Soc Neuroscience
Transcutaneous auricular vagus nerve stimulation (taVNS) has been proposed to activate
the locus ceruleus-noradrenaline (LC-NA) system. However, previous studies failed to find …

A review of parameter settings for invasive and non-invasive vagus nerve stimulation (VNS) applied in neurological and psychiatric disorders

SL Thompson, GH O'Leary, CW Austelle… - Frontiers in …, 2021 - frontiersin.org
Vagus nerve stimulation (VNS) is an established form of neuromodulation with a long history
of promising applications. Earliest reports of VNS in the literature date to the late 1800's in …

[HTML][HTML] Vagus nerve stimulation induces widespread cortical and behavioral activation

L Collins, L Boddington, PJ Steffan, D McCormick - Current Biology, 2021 - cell.com
Vagus nerve stimulation (VNS) is used for management of a variety of neurological
conditions, although the therapeutic mechanisms are not fully understood. Accumulating …

When the locus coeruleus speaks up in sleep: recent insights, emerging perspectives

A Osorio-Forero, N Cherrad, L Banterle… - International journal of …, 2022 - mdpi.com
For decades, numerous seminal studies have built our understanding of the locus coeruleus
(LC), the vertebrate brain's principal noradrenergic system. Containing a numerically small …