The neutron instruments suite, installed at the spallation neutron source of the Materials and
Life Science Experimental Facility (MLF) at the Japan Proton Accelerator Research Complex …

Chemists have long sought to mimic enzymatic hydrogen activation with structurally simpler
compounds. Here, we report a functional [NiFe]-based model of [NiFe] hydrogenase …

Hydrogen atoms and hydration water molecules in proteins are indispensable for many
biochemical processes, especially enzymatic catalysis. The locations of hydrogen atoms in …

Hydrolysis of carbohydrates is a major bioreaction in nature, catalyzed by glycoside
hydrolases (GHs). We used neutron diffraction and high-resolution x-ray diffraction analyses …

Neutron crystallography offers enormous potential to complement structures from X-ray
crystallography by clarifying the positions of low-Z elements, namely hydrogen …

The first high-resolution neutron protein structure of perdeuterated rubredoxin from
Pyrococcus furiosus (PfRd) determined using the new IMAGINE macromolecular neutron …

SENJU is a new single-crystal time-of-flight neutron diffractometer installed at BL18 at the
Materials and Life Science Experimental Facility of the Japan Accelerator Research …

Copper-containing nitrite reductases (CuNIRs) transform nitrite to gaseous nitric oxide,
which is a key process in the global nitrogen cycle. The catalytic mechanism has been …

The planarity of the peptide bond is important for the stability and structure formation of
proteins. However, substantial distortion of peptide bonds has been reported in several high …

Transthyretin (TTR) is a tetrameric protein associated with human amyloidosis. In vitro, the
formation of amyloid fibrils by TTR is known to be promoted by low pH. Here we show the …