Genome-wide association studies (GWAS) for BMI, waist-to-hip ratio, and other adiposity
traits have identified more than 300 single-nucleotide polymorphisms (SNPs). Although …

There is a genetic component to human obesity that accounts for 40% to 50% of the
variability in body weight status but that is lower among normal weight individuals (about …

In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

Background Obesity is a global health problem mainly attributed to lifestyle changes such as
diet, low physical activity or socioeconomics factors. However, several evidences …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta …

To increase our understanding of the genetic basis of adiposity and its links to
cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of …

Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …

Here we summarize the latest data on genetic and epigenetic contributions to human aging
and longevity. Whereas environmental and lifestyle factors are important at younger ages …

Elevated body mass index (BMI) associates with cardiometabolic traits on observational
analysis, yet the underlying causal relationships remain unclear. We conducted Mendelian …

Recent genetic association studies have identified 55 genetic loci associated with obesity or
body mass index (BMI). The vast majority, 51 loci, however, were identified in European …