Genetics of chronic respiratory disease

I Sayers, C John, J Chen, IP Hall - Nature Reviews Genetics, 2024 - nature.com
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD),
asthma and interstitial lung diseases are frequently occurring disorders with a polygenic …

Pathophysiology and genomics of bronchiectasis

L Perea, R Faner, JD Chalmers… - European Respiratory …, 2024 - err.ersjournals.com
Bronchiectasis is a complex and heterogeneous inflammatory chronic respiratory disease
with an unknown cause in around 30–40% of patients. The presence of airway infection …

Preclinical murine models for the testing of antimicrobials against Mycobacterium abscessus pulmonary infections: Current practices and recommendations

V Dartois, TL Bonfield, JP Boyce, CL Daley, T Dick… - Tuberculosis, 2024 - Elsevier
Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, is
increasingly recognized as an important pathogen of the human lung, disproportionally …

Rethinking bronchiectasis as an inflammatory disease

MB Long, SH Chotirmall, M Shteinberg… - The Lancet …, 2024 - thelancet.com
Bronchiectasis is understood to be the result of a complex interaction between infection,
impaired mucociliary clearance, inflammation, and lung damage. Current therapeutic …

Cough in Non-Cystic Fibrosis Bronchiectasis

A Kantar, WJ Song, A Bush… - ERJ Open …, 2024 - Eur Respiratory Soc
Non-cystic fibrosis bronchiectasis (NCFBE) belongs to the spectrum of chronic suppurative
lung diseases and is characterised by persistent wet/sputum-productive cough and airway …

Small Airways in Non–Cystic Fibrosis Bronchiectasis

JD Dickinson, CM Evans, BF Dickey - American journal of …, 2024 - atsjournals.org
Supported by grants from the US National Institutes of Health (R01 HL157269 to JDD, R01
HL130938 and P01 HL162607 to CME, R01 HL080396 to CME and BFD, and R01 …