Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction

L Ge, K Wang, H Lin, E Tao, W Xia, F Wang… - … in bioengineering and …, 2023 - frontiersin.org
The tissue reconstruction of diabetic wounds mainly depends on the proliferation and
remodelling of cutaneous cells around wounds and the transplantation of random skin flaps …

Exploring Endothelial Colony‐Forming Cells to Better Understand the Pathophysiology of Disease: An Updated Review

Q Zhang, A Cannavicci, MJB Kutryk - Stem Cells International, 2022 - Wiley Online Library
Endothelial cell (EC) dysfunction has been implicated in a variety of pathological conditions.
The collection of ECs from patients is typically conducted postmortem or through invasive …

Insulin-Induced Gene 1-Enhance Secretion of BMSC Exosome Enriched in miR-132–3p Promoting Wound Healing in Diabetic Mice

L Zheng, H Song, Y Li, H Li, G Lin… - Molecular …, 2024 - ACS Publications
Chronic diabetic wounds represent a significant clinical challenge because of impaired
healing processes, which require innovative therapeutic strategies. This study explores the …

[HTML][HTML] Exosomal microRNA-Based therapies for skin diseases

C Jibing, L Weiping, Y Yuwei, F Bingzheng… - Regenerative …, 2024 - Elsevier
Based on engineered cell/exosome technology and various skin-related animal models,
exosomal microRNA (miRNA)-based therapies derived from natural exosomes have shown …

The potential role of MiRs-139-5p and-454-3p in endoglin-knockdown-induced angiogenic dysfunction in HUVECs

A Cannavicci, Q Zhang, MJB Kutryk - International journal of molecular …, 2023 - mdpi.com
Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disease characterized by
aberrant angiogenesis and vascular malformations. Mutations in the transforming growth …