Duration of untreated illness as a key to early intervention in schizophrenia: a review

A Murru, B Carpiniello - Neuroscience letters, 2018 - Elsevier
The first psychotic episode is classically viewed as a critical period which management is
important in determining the long-term outcome of the schizophrenia (SCZ). For this reason …

Die psychische Gesundheit von Kindern, Jugendlichen und jungen Erwachsenen–Teil 1: Häufigkeit, Störungspersistenz, Belastungsfaktoren, Service …

M Lambert, T Bock, D Naber, B Löwe… - Fortschritte der …, 2013 - thieme-connect.com
In einer Vielzahl von Geburtskohortenstudien, epidemiologischen Studien und klinischen
Beobachtungsstudien wurden psychische Erkrankungen bei Kindern, Jugendlichen und …

Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated …

F Briend, EA Nelson, O Maximo, WP Armstrong… - Translational …, 2020 - nature.com
Evidence points toward a relationship between longer duration of untreated psychosis
(DUP) and worse long-term outcomes in patients with first episode psychosis (FEP), but the …

White matter integrity, duration of untreated psychosis, and antipsychotic treatment response in medication-naïve first-episode psychosis patients

NV Kraguljac, T Anthony, CJ Morgan, RD Jindal… - Molecular …, 2021 - nature.com
It is becoming increasingly clear that longer duration of untreated psychosis (DUP) is
associated with adverse clinical outcomes in patients with psychosis spectrum disorders …

From hospital to the community: The influence of deinstitutionalization on discharged long‐stay psychiatric patients

N Kunitoh - Psychiatry and clinical neurosciences, 2013 - Wiley Online Library
The aim of the present study is to clarify the influence of deinstitutionalization on discharged
long‐stay patients based on a review of recently published literature. E nglish‐language …

Converging evidence points to BDNF as biomarker of depressive symptoms in schizophrenia-spectrum disorders

M Manchia, U Isayeva, R Collu, D Primavera, L Deriu… - Brain sciences, 2022 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is a key modulator of neuroplasticity and has an
important role in determining the susceptibility to severe psychiatric disorder with a …

The report of the joint WPA/CINP workgroup on the use and usefulness of antipsychotic medication in the treatment of schizophrenia

KN Fountoulakis, HJ Moeller, S Kasper… - CNS …, 2021 - cambridge.org
This is a report of a joint World Psychiatric Association/International College of
Neuropsychopharmacology (WPA/CINP) workgroup concerning the risk/benefit ratio of …

Staging of schizophrenia with the use of PANSS: an international multi-center study

KN Fountoulakis, E Dragioti… - International Journal …, 2019 - academic.oup.com
Introduction A specific clinically relevant staging model for schizophrenia has not yet been
developed. The aim of the current study was to evaluate the factor structure of the PANSS …

Violence and mental disorders. A retrospective study of people in charge of a community mental health center

F Pinna, M Tusconi, C Dessì, G Pittaluga… - International journal of …, 2016 - Elsevier
Background Numerous studies conducted in inpatient settings have highlighted how mental
disorders are associated with an increased risk of violence, particularly during acute phases …

Patterns and determinants of treatment seeking among previously untreated psychotic patients in Aceh Province, Indonesia: a qualitative study

M Marthoenis, MC Aichberger, M Schouler-Ocak - Scientifica, 2016 - Wiley Online Library
Immediate treatment of first‐episode psychosis is essential in order to achieve a positive
outcome. However, Indonesian psychiatric patients often delay accessing health services …