Multiple myeloma (MM) is a cancer of plasma cells that has been extensively studied in
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …

Abstract High oxidative stress, Th1/Th17 immune response, M1 macrophage inflammation,
and cell death are associated with cardiovascular diseases. Controlled oxidative stress …

Simple Summary Cancer onset and progression are promoted by high deregulation of the
immune system. Recently, major advances in molecular and clinical cancer immunology …

Multiple myeloma (MM) is a malignant disease of plasma cells with complex pathology,
causing significant morbidity due to its end-organ destruction. The outcomes of patients with …

Dysregulated hematopoietic niches remodeled by leukemia cells lead to imbalances in
immunological mediators that support leukemogenesis and drug resistance. Targeting …

Th17 and Treg cells play an important role in regulating tissue inflammation and maintaining
the stability of the immune system. They regulate inflammatory responses, participate in the …

Simple Summary The growing interest in immunotherapy for the treatment of multiple
myeloma demands a deep knowledge of the complex interactions between malignant and …

Nowadays, new advances in society and health have brought an increased life expectancy.
However, at the same time, aging comes with complications that impact the development of …

Background Multiple myeloma (MM) is a hematologic malignancy characterized by high
genomic instability, and telomere dysfunction is an important cause of acquired genomic …

Pyroptosis is a novel form of programmed cell death (PCD), which is characterized by DNA
fragmentation, chromatin condensation, cell swelling and leakage of cell contents. The …