Gestational diabetes mellitus (GDM), characterized by a transitory form of diabetes induced
by insulin resistance and pancreatic β-cell dysfunction during pregnancy, has been …

Abstract Purpose of Review To summarize recent literature relating early-life environmental
exposures on DNA methylation in the placenta, to identify how variation in placental …

Background Autism spectrum disorder (ASD) involves complex genetics interacting with the
perinatal environment, complicating the discovery of common genetic risk. The epigenetic …

In utero exposure to maternal tobacco smoking is the leading cause of birth complications in
addition to being associated with later impairment in child's development. Epigenetic …

Although male–female differences in placental structure and function have been observed,
little is understood about their molecular underpinnings. Here, we present a mega-analysis …

Here, we report a lack of diversity in epigenome-wide association studies (EWAS) and DNA
methylation (DNAm) data, discuss current challenges, and propose solutions for EWAS and …

Childhood trauma (CT) is well established as a potent risk factor for the development of
mental disorders. However, the potential of adverse early experiences to exert chronic and …

Background Human placental DNA methylation (DNAme) data is a valuable resource for
studying sex differences during gestation, as DNAme profiles after delivery reflect the …

Background Genome-wide DNA methylation (DNAme) profiling of the placenta with Illumina
Infinium Methylation bead arrays is often used to explore the connections between in utero …

DNA methylation is an ideal trait to study the extent of the shared genetic control across
ancestries, effectively providing hundreds of thousands of model molecular traits with large …