Multi‐cellular spheroids are formed as a 3D structure with dense cell–cell/cell–extracellular
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …

Cell sheet technology has remained quite popular among tissue engineering techniques
over the last several years. Meanwhile, there is an apparent trend in modern scientific …

In this work a dual crosslinked network based on sodium alginate graft copolymer, bearing
poly (N-isopropylacrylamide-co-N-tert-butylacrylamide) P (NIPAM-co-NtBAM) side chains …

A spheroid is a complex, spherical cellular aggregate supporting cell-cell and cell-matrix
interactions in an environment that mimics the real-world situation. In terms of tissue …

Background Adipose-derived stem cell (ASC) has been considered as a desirable source
for cell therapy. In contrast to combining scaffold materials with cells, ASCs can be fabricated …

Breast cancer progression is a complex process involving the primary tumor and its
microenvironment supported by a vascular network. Multicellular spheroids closely mimic in …

Organotypic micrometre-size 3D aggregates of skin cells (multicellular spheroids) have
emerged as a promising in vitro model that can be utilized as an alternative of animal …

Cell spheroids as building blocks for engineering micro-tissue should be able to mimic the
complex structure of natural tissue. However, control of the distribution of multiple cell …

The incidence of treatment of thyroid disease and consequential hypothyroidism has been
increasing over the past few years. To maintain adequate thyroid hormone levels, these …

Abstract 3D cell cultures are becoming the new standard for cell-based in vitro research, due
to their higher transferrability toward in vivo biology. The lack of established techniques for …