Non-invasive preimplantation genetic testing (niPGT): the next revolution in reproductive genetics?

M Leaver, D Wells - Human reproduction update, 2020 - academic.oup.com
BACKGROUND Preimplantation genetic testing (PGT) encompasses methods that allow
embryos to be tested for severe inherited conditions or for chromosome abnormalities …

The impact of biopsy on human embryo developmental potential during preimplantation genetic diagnosis

D Cimadomo, A Capalbo, FM Ubaldi… - BioMed research …, 2016 - Wiley Online Library
Preimplantation Genetic Diagnosis and Screening (PGD/PGS) for monogenic diseases
and/or numerical/structural chromosomal abnormalities is a tool for embryo testing aimed at …

Preimplantation genetic testing for aneuploidy by microarray analysis of polar bodies in advanced maternal age: a randomized clinical trial

W Verpoest, C Staessen, PM Bossuyt… - Human …, 2018 - academic.oup.com
STUDY QUESTION Does preimplantation genetic testing for aneuploidy (PGT-A) by
comprehensive chromosome screening (CCS) of the first and second polar body to select …

Time-lapse parameters as predictors of blastocyst development and pregnancy outcome in embryos from good prognosis patients: a prospective cohort study

K Kirkegaard, US Kesmodel, JJ Hindkjær… - Human …, 2013 - academic.oup.com
STUDY QUESTION Do early time-lapse parameters predict which embryos will develop to
high-quality blastocysts and does timing of development differ between embryos that implant …

Preimplantation genetic diagnosis: state of the art 2011

JC Harper, SB SenGupta - Human genetics, 2012 - Springer
For the last 20 years, preimplantation genetic diagnosis (PGD) has been mostly performed
on cleavage stage embryos after the biopsy of 1–2 cells and PCR and FISH have been used …

ESHRE PGD Consortium/Embryology Special Interest Group—best practice guidelines for polar body and embryo biopsy for preimplantation genetic diagnosis …

GL Harton, MC Magli, K Lundin, M Montag… - Human …, 2011 - academic.oup.com
Abstract In 2005, the European Society for Human Reproduction and Embryology (ESHRE)
Preimplantation Genetic Diagnosis (PGD) Consortium published a set of Guidelines for Best …

[HTML][HTML] Assisted reproductive technology after the birth of Louise Brown

RM Kamel - Journal of reproduction & infertility, 2013 - ncbi.nlm.nih.gov
Background Public interest in Assisted Reproductive Technology (ART) has remained high
since the birth of the world's first in vitro fertilization baby, Louise Brown, in the United …

Blastocyst biopsy versus cleavage stage biopsy and blastocyst transfer for preimplantation genetic diagnosis of β-thalassaemia: a pilot study

G Kokkali, J Traeger-Synodinos, C Vrettou… - Human …, 2007 - academic.oup.com
BACKGROUND Trophectoderm biopsy at the blastocyst stage is an emerging approach in
preimplantation genetic diagnosis (PGD). This study aimed to compare genotyping success …

DNA methylome reveals cellular origin of cell-free DNA in spent medium of human preimplantation embryos

Y Chen, Y Gao, J Jia, L Chang, P Liu… - The Journal of …, 2021 - Am Soc Clin Investig
The discovery of embryonic cell–free DNA (cfDNA) in spent embryo culture media (SECM)
has brought hope for noninvasive preimplantation genetic testing. However, the cellular …

Preimplantation genetic screening and preimplantation genetic diagnosis

C Sullivan-Pyke, A Dokras - Obstetrics and Gynecology …, 2018 - obgyn.theclinics.com
Infertility affects 7.5 million women in the United States, and approximately 1 in 8 couples
have difficulty conceiving or sustaining a pregnancy. 1 In vitro fertilization (IVF) is a …