A bidirectional relationship exists between adipose tissue metabolism and iron regulation.
Total body fat, fat distribution and exercise influence iron status and components of the iron …

Iron is vital for many physiological functions, including energy production, and dysregulated
iron homeostasis underlies a number of pathologies. Ferroptosis is a recently recognized …

Lysosomes are the primary degradative compartment within cells and there have been
significant advances over the past decade toward understanding how lysosome …

The biggest drawback of a current diabetes therapy is the treatment of the consequences not
the cause of the disease. Regardless of the diabetes type, preservation and recovery of …

Dietary iron assimilation is critical for health and essential to prevent iron-deficient states
and related comorbidities, such as anemia. The bioavailability of iron is generally low, while …

Autophagy is the primary catabolic program of the cell that promotes survival in response to
metabolic stress. It is tightly regulated by a suite of kinases responsive to nutrient status …

Iron imbalance in the brain negatively affects brain function. With aging, iron levels increase
in the brain and contribute to brain damage and neurological disorders. Changes in the …

During oxidative stress neurons release lipids that are internalized by glia. Defects in this
coordinated process play an important role in several neurodegenerative diseases. Yet, the …

Purpose Mulberry leaf extract has exerted better antidiabetic activities, while the effects of
major active components in mulberry leaf extract are still unclear. Cryptochlorogenic acid …

Iron overload is associated with various pathological changes which contribute to metabolic
syndrome, many of which have been proposed to occur via damaging tissue through an …