The life of U6 small nuclear RNA, from cradle to grave
AL Didychuk, SE Butcher, DA Brow - Rna, 2018 - rnajournal.cshlp.org
Removal of introns from precursor messenger RNA (pre-mRNA) and some noncoding
transcripts is an essential step in eukaryotic gene expression. In the nucleus, this process of …
transcripts is an essential step in eukaryotic gene expression. In the nucleus, this process of …
Structure of spliceosomal snRNPs and their role in pre-mRNA splicing
R Lührmann, B Kastner, M Bach - … et Biophysica Acta (BBA)-Gene Structure …, 1990 - Elsevier
Many eucaryotic genes which encode messenger RNA are split genes; that is, the protein
coding sequences,(exons), are interrupted by non-coding sequences (introns). Expression …
coding sequences,(exons), are interrupted by non-coding sequences (introns). Expression …
Programmable base editing of A• T to G• C in genomic DNA without DNA cleavage
The spontaneous deamination of cytosine is a major source of transitions from C• G to T• A
base pairs, which account for half of known pathogenic point mutations in humans. The …
base pairs, which account for half of known pathogenic point mutations in humans. The …
Spliceosomal RNA U6 is remarkably conserved from yeast to mammals
DA Brow, C Guthrie - Nature, 1988 - nature.com
The small nuclear RNA U6 and its gene have been isolated from yeast. In striking contrast to
other yeast spliceosomal RNAs, U6 is very similar in size, sequence and structure to its …
other yeast spliceosomal RNAs, U6 is very similar in size, sequence and structure to its …
Splicing of messenger RNA precursors
PA Sharp - Science, 1987 - science.org
A general mechanism for the splicing of nuclear messenger RNA precursors in eukaryotic
cells has been widely accepted. This mechanism, which generates lariat RNAs possessing …
cells has been widely accepted. This mechanism, which generates lariat RNAs possessing …
Sibling Species in Montastraea annularis, Coral Bleaching, and the Coral Climate Record
Measures of growth and skeletal isotopic ratios in the Caribbean coral Montastraea
annularis are fundamental to many studies of paleoceanography, environmental …
annularis are fundamental to many studies of paleoceanography, environmental …
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes
MM Konarska, PA Sharp - Cell, 1987 - cell.com
Electrophoretic separation of ribonucleoprotein particles in a nondenaturing gel was used to
analyze the splicing of mRNA precursors. Early in the reaction, a complex formed consisting …
analyze the splicing of mRNA precursors. Early in the reaction, a complex formed consisting …
Structural analyses of EBER1 and EBER2 ribonucleoprotein particles present in Epstein-Barr virus-infected cells
JN Glickman, JG Howe, JA Steitz - Journal of virology, 1988 - Am Soc Microbiol
The ribonucleoprotein (RNP) particles containing the Epstein-Barr virus-associated small
RNAs EBER1 and EBER2 were analyzed to determine their RNA secondary structures and …
RNAs EBER1 and EBER2 were analyzed to determine their RNA secondary structures and …
Modification of U6 spliceosomal RNA is guided by other small RNAs
KT Tycowski, ZH You, PJ Graham, JA Steitz - Molecular cell, 1998 - cell.com
The vertebrate spliceosomal snRNAs are highly modified by pseudouridylation and 2′-O-
methylation. We have identified novel conserved small RNAs that can direct addition of two …
methylation. We have identified novel conserved small RNAs that can direct addition of two …
[图书][B] DNA and RNA modification enzymes: structure, mechanism, function and evolution
H Grosjean - 2009 - taylorfrancis.com
This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …
modification-editing processes and to some extent repair mechanisms. Each chapter offers …