Statins are a cornerstone in the pharmacological prevention of cardiovascular disease.
Although generally well tolerated, a small subset of patients experience statin-related …

Adverse drug reactions (ADR) remain the major problems in healthcare. Most severe ADR
are unpredictable, dose-independent and termed as type B idiosyncratic reactions. Recent …

What is known and objective Statins are widely used worldwide in the prevention and
treatment of coronary atherosclerotic heart disease and ischaemic stroke. However, in …

Introduction: Statins remain the most commonly prescribed lipid-lowering drug class for the
treatment of atherosclerotic cardiovascular disease. Their well-recognized side effects are …

This meta-analysis was conducted to determine the genotypic effects of rs4149056 and
rs2306283 polymorphism in SLCO1B1 gene on myopathy in patients with statin. Studies …

Statins, a class of lipid-lowering medications, have been a keystone treatment in
cardiovascular health. However, adverse effects associated with statin use impact patient …

Most of the prescribing and dispensing of medicines happens in primary care.
Pharmacogenomics (PGx) is the study and clinical application of the role of genetic variation …

Statins can be associated with myopathy. We have undertaken a genomewide association
study (GWAS) to discover and validate genetic risk factors for statin‐induced myopathy in a …

The objective of this study was to characterize clinician response following standardization
of pharmacogenetic (PGx) clinical decision support alerts at University of Florida (UF) …

Objective Statins are the first-choice therapy for dyslipidemia, but their effectiveness can be
influenced by genetic polymorphisms. This study was conducted to assess the association of …