Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …

LH and chorionic gonadotropin (CG) are glycoproteins fundamental to sexual development
and reproduction. Because they act on the same receptor (LHCGR), the general consensus …

Innate immune signaling is essential for clearing pathogens and damaged cells and must be
tightly regulated to avoid excessive inflammation or autoimmunity. Here, we found that the …

This paper concerns 3′-untranslated regions (3′ UTRs) of mRNAs, which are non-coding
regulatory platforms that control stability, fate and the correct spatiotemporal translation of …

Transposable elements (TEs) are major components of all vertebrate genomes that can
cause deleterious insertions and genomic instability. However, depending on the specific …

The glycoprotein hormones (GPH) are heterodimers composed of a common α subunit and
a specific β subunit. They act by activating specific leucine-rich repeat G protein-coupled …

G protein–coupled receptors (GPCRs) play an important role in physiology and disease and
represent the most productive drug targets. Orphan GPCRs, with their endogenous ligands …

The realization that body parts of animals and plants can be recruited or coopted for novel
functions dates back to, or even predates the observations of Darwin. SJ Gould and ES Vrba …

Alu repeats contribute to phylogenetic novelties in conserved regulatory networks in
primates. Our study highlights how exonized Alus could nucleate large-scale mRNA–miRNA …

G protein-coupled receptors (GPCRs) play an important role in physiology and disease and
represent productive drug targets. Orphan GPCRs, which have unknown endogenous …