The NK-92 cell line, established in 1992, mirrors all the characteristics of highly active blood
natural killer (NK) cells but with much broader and greater cytotoxicity. The cell line was …

Natural killer (NK) cells are innate lymphocytes that recognize and clear infected and
transformed cells. The importance of NK cells in tumor surveillance underlies the …

Chimeric antigen receptor (CAR)-modified natural killer (NK) cells show antileukemic activity
against acute myeloid leukemia (AML) in vivo. However, NK cell-mediated tumor killing is …

Immunotherapy based on natural killer (NK) cells is a promising approach for treating a
variety of cancers. Unlike T cells, NK cells recognize target cells via a major …

Abstract Treatment for renal cell carcinoma (RCC) has improved dramatically over the last
decade, shifting from high-dose cytokine therapy in combination with surgical resection of …

Introduction Metastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades
conventional treatments and endogenous antitumor immune responses, highlighting the …

Human Natural Killer (NK) cells are all round players in immunity thanks to their powerful
and immediate response against transformed cells and the ability to modulate the …

In recent years, immunotherapy for cancer has become mainstream with several products
now authorized for therapeutic use in the clinic and are becoming the standard of care for …

Background: Natural killer (NK) cells are crucial components of the innate immune system
that fight tumors and viral infections. Patients with colorectal cancer (CRC) have a poor …

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a potentially curative
treatment for patients with high-risk acute leukemias, but unfortunately disease recurrence …