Clathrin-mediated endocytosis occurs via the assembly of clathrin-coated pits (CCPs) that
invaginate and pinch off to form clathrin-coated vesicles (CCVs). It is well known that adaptor …

Although essential for many cellular processes, the sequence of structural and molecular
events during clathrin-mediated endocytosis remains elusive. While it was long believed that …

In recent years, there has been considerable push toward the biomedical applications with
active particles, which have great potential to revolutionize disease diagnostics and therapy …

Many intracellular pathogens, such as mammalian reovirus, mimic extracellular matrix motifs
to specifically interact with the host membrane. Whether and how cell-matrix interactions …

Nanomedicine aims to increase the effectiveness of therapeutic and diagnostic agents by
exploiting unique properties that arise when operating at the nanoscale. Despite the recent …

The cellular uptake of nanoparticles or viruses requires that the gain of adhesion energy
overcomes the cost of plasma membrane bending. It is well known that this leads to a …

Clathrin-mediated endocytosis is the major pathway by which eukaryotic cells take up
extracellular material, but it is still elusive which physical pathways are being taken during …

Nanoparticles have been extensively adopted to deliver therapeutic drug molecules to cells
through clathrin-mediated endocytosis (CME). The size and shape of nanoparticles are …

Receptor-mediated endocytosis requires that the energy of adhesion overcomes the
deformation energy of the plasma membrane. The resulting driving force is balanced by …

Clathrin-mediated endocytosis is the main pathway used by eukaryotic cells to take up
extracellular material, but the dominant physical mechanisms driving this process are still …