Cystic fibrosis is a hereditary disease that mainly affects secretory organs in humans. It is
caused by mutations in the gene encoding CFTR with the most common phenylalanine …

Once thought of in terms of bioenergetics, mitochondria are now widely accepted as both the
orchestrator of cellular health and the gatekeeper of cell death. The pulmonary disease field …

The aim of this review article is to collate recent contributions of proteomic studies to cystic
fibrosis transmembrane conductance regulator (CFTR) biology. We summarize advances …

Sepsis leads to the damage of multiple organs, and thereby adversely affects the
cardiovascular system. At present, no effective method has been found to treat myocardial …

Poor nutrition in people with Cystic Fibrosis (CF) is associated with poor clinical outcomes
and early intervention is essential for normal growth, development and to ensure clinical …

Disordered sleep experienced by people with cystic fibrosis (CF) suggest a possible
disruption in circadian regulation being associated with the loss of cystic fibrosis …

Choice of vector is the most critical step in gene therapy. Adeno-associated viruses (AAV);
third generation vectors, are getting much attention of scientists to be used as vehicles due …

The ε 4 allele of the apolipoprotein E gene (APOE4) constitutes the main genetic risk factor
for late-onset Alzheimer disease (AD). High amounts of pure apolipoprotein E4 (ApoE4), in a …

Sarcopenia, characterized by decreased muscle mass and strength, is associated with
aging. In clinics, there are few effective options for treating sarcopenia. Cystic fibrosis …