Hyperthyroidism: aetiology, pathogenesis, diagnosis, management, complications, and prognosis

WM Wiersinga, KG Poppe… - The lancet Diabetes & …, 2023 - thelancet.com
Hyperthyroidism is a common condition with a global prevalence of 0· 2–1· 3%. When
clinical suspicion of hyperthyroidism arises, it should be confirmed by biochemical tests (eg …

Graves' disease: can it be cured?

WM Wiersinga - Endocrinology and Metabolism, 2019 - synapse.koreamed.org
Whether or not Graves' hyperthyroidism can be really cured, depends on the definition of
“cure.” If eradication of thyroid hormone excess suffices for the label “cure,” then all patients …

Management of Graves' hyperthyroidism: present and future

L Bartalena, E Piantanida, D Gallo… - Expert Review of …, 2022 - Taylor & Francis
Introduction Graves' disease (GD) is an autoimmune disorder due to loss of tolerance to the
thyrotropin receptor (TSHR) and ultimately caused by stimulatory TSHR antibodies (TSHR …

Approach to the patient considering long-term antithyroid drug therapy for Graves' disease

F Azizi, L Mehran, H Abdi… - The Journal of Clinical …, 2024 - academic.oup.com
Antithyroid drugs (ATD) are the treatment of choice for the majority of patients with Graves'
hyperthyroidism worldwide. However, relapse of hyperthyroidism after withdrawal of …

Pathophysiology of thyroid-associated orbitopathy

ACH Lee, GJ Kahaly - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Thyroid-associated orbitopathy, the most common extrathyroidal manifestation of Graves'
disease, is characterized by orbital inflammatory infiltration and activation of orbital …

Antithyroid drug treatment for Graves' disease: baseline predictive models of relapse after treatment for a patient-tailored management

E Masiello, G Veronesi, D Gallo, P Premoli… - Journal of …, 2018 - Springer
Abstract Background Antithyroid drugs (ATDs) are first-line treatment for Graves'
hyperthyroidism worldwide, but relapses are frequent. The reliability of individual risk factors …

Risk factors for the relapse of Graves' disease treated with antithyroid drugs: a systematic review and meta-analysis

HE Shi, R Sheng, Y Hu, X Liu, L Jiang, Z Wang… - Clinical …, 2020 - Elsevier
Abstract Purpose Antithyroid drugs (ATDs) are the first-line treatment for Graves' disease
(GD). A common problem with ATD treatment is the high relapse rate after drug withdrawal …

The long-term follow-up of patients with thionamide-treated Graves' hyperthyroidism

S Bandai, K Okamura, M Fujikawa, K Sato… - Endocrine …, 2019 - jstage.jst.go.jp
Since there have been few reports on the long-term prognosis of Graves' hyperthyroidism,
the prognosis of 549 Graves' hyperthyroidism patients initially treated with thionamide and …

Efficacy of Anti-Thyroid Medications in Patients with Graves' Disease

MM Mahzari, MM Alanazi, YM Alabdulkareem… - BMC Endocrine …, 2024 - Springer
Introduction Graves' disease (GD) is an autoimmune disorder characterized by
hyperthyroidism due to increased thyroid-stimulating hormone receptor antibodies (TRAb) …

[HTML][HTML] Comparison of two different TSH-receptor antibody assays: A clinical practice study

M van Balkum, MWJ Schreurs, WE Visser, RP Peeters… - Heliyon, 2023 - cell.com
Background Graves' disease (GD) is caused by the production of TSH-receptor (TSHR)
stimulating auto-antibodies. Over the years various TSHR-antibody (TRAb) detection assays …