Marine organisms have been shown to be a valuable source for biologically active
compounds for the prevention and treatment of cancer, inflammation, immune system …

In recent years, several antibody drug conjugates (ADC) have been accepted by the FDA as
therapeutics against cancer. It is well‐known that control of drug‐to‐antibody ratio (DAR) is …

Abstract Rationale: As a cancer, Glioblastoma (GBM) is a highly lethal and difficult-to-treat.
With the aim of improving therapies to GBM, we developed novel and target-specific …

Globally, despite clinical advancements made over a decade, cancer remains a prominent
cause of death. Numerous drugs have been chemically synthesized to cure this disorder …

DNA nanostructures have considerable biomedical potential as intracellular delivery
vehicles as they are highly homogeneous and can be functionalized with high spatial …

Synthetic analogs based on the DNA bis-intercalating natural product peptides sandramycin
and quinaldopeptin were investigated as antibody drug conjugate (ADC) payloads …

In spite of significant progress in the field of targeted anticancer therapy, the FDA has
approved only five ADC-based drugs. Hence the search for new targeted anticancer agents …

Monomethyl auristatin E and monomethyl auristatin F are widely used cytotoxic agents in
antibody–drug conjugates (ADCs), a group of promising cancer drugs. The ADCs …

Halogenation can be utilized for the purposes of labeling and molecular imaging, providing
a means to, eg, follow drug distribution in an organism through positron emission …

Although the percentage of cancer survivors has increased over time, cancer remains the
second leading cause of death worldwide. Chemotherapy, a common approach to treating …