Nanomaterials for theranostics: recent advances and future challenges
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …
Design strategies for water-soluble small molecular chromogenic and fluorogenic probes
X Li, X Gao, W Shi, H Ma - Chemical reviews, 2014 - ACS Publications
Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …
Selective visualization of the endogenous peroxynitrite in an inflamed mouse model by a mitochondria-targetable two-photon ratiometric fluorescent probe
Peroxynitrite (ONOO–) is a kind of reactive oxygen species (ROS) with super activity of
oxidization and nitration, and overproduction of ONOO–is associated with pathogenesis of …
oxidization and nitration, and overproduction of ONOO–is associated with pathogenesis of …
Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
The dynamic chemical diversity of elements, ions and molecules that form the basis of life
offers both a challenge and an opportunity for study. Small-molecule fluorescent probes can …
offers both a challenge and an opportunity for study. Small-molecule fluorescent probes can …
Super-resolution imaging of mitochondrial HClO during cell ferroptosis using a near-infrared fluorescent probe
Ferroptosis is of great importance in physiological and pathological processes, which is
associated with various inflammation-related diseases, cardiovascular diseases, and even …
associated with various inflammation-related diseases, cardiovascular diseases, and even …
19F Magnetic Resonance Imaging (MRI): From Design of Materials to Clinical Applications
I Tirotta, V Dichiarante, C Pigliacelli, G Cavallo… - Chemical …, 2015 - ACS Publications
To enable early monitoring of various diseases, to develop noninvasive diagnostic tools,
and to implement targeted therapies are some of the major challenges in current medicine …
and to implement targeted therapies are some of the major challenges in current medicine …
An “enhanced PET”-based fluorescent probe with ultrasensitivity for imaging basal and elesclomol-induced HClO in cancer cells
Reactive oxygen species (ROS) and cellular oxidant stress have long been associated with
cancer. Unfortunately, the role of HClO in tumor biology is much less clear than for other …
cancer. Unfortunately, the role of HClO in tumor biology is much less clear than for other …
[HTML][HTML] Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles
Inflammation is a pivotal driver of atherosclerotic plaque progression and rupture and is a
target for identifying vulnerable plaques. However, challenges arise with the current in vivo …
target for identifying vulnerable plaques. However, challenges arise with the current in vivo …
Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species
X Chen, X Tian, I Shin, J Yoon - Chemical Society Reviews, 2011 - pubs.rsc.org
Oxidative and nitrosative stress induced by ROS/RNS play crucial roles in a wide range of
physiological processes and are also implicated in various diseases, including cancer and …
physiological processes and are also implicated in various diseases, including cancer and …
ROS production in phagocytes: why, when, and where?
S Dupré-Crochet, M Erard… - Journal of leukocyte …, 2013 - academic.oup.com
In the phagocytosis field, ROS production by the phagocyte NOX has been associated with
pathogen killing for the last 50 years. Since the discovery of nonphagocyte NOX, numerous …
pathogen killing for the last 50 years. Since the discovery of nonphagocyte NOX, numerous …