A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions

T Hughes, T Bracewell-Milnes, S Saso… - Human …, 2021 - academic.oup.com
BACKGROUND In pre-implantation genetic testing (PGT), fertile couples undergo IVF with
genetic testing of embryos to avoid conceptions with a genetic condition. There is an …

Review of patient decision‐making factors and attitudes regarding preimplantation genetic diagnosis

MC Genoff Garzon, LR Rubin, M Lobel… - Clinical …, 2018 - Wiley Online Library
The increasing technical complexity and evolving options for repro‐genetic testing have
direct implications for information processing and decision making, yet the research among …

Reproductive issues in carriers of germline pathogenic variants in the BRCA1/2 genes: an expert meeting

B Buonomo, C Massarotti, M Dellino, P Anserini… - BMC medicine, 2021 - Springer
Background Healthy individuals and patients with cancer who are carriers of germline
pathogenic variants in the BRCA1/2 genes face multiple reproductive challenges that …

Utility of polygenic embryo screening for disease depends on the selection strategy

T Lencz, D Backenroth, E Granot-Hershkovitz, A Green… - Elife, 2021 - elifesciences.org
Polygenic risk scores (PRSs) have been offered since 2019 to screen in vitro fertilization
embryos for genetic liability to adult diseases, despite a lack of comprehensive modeling of …

[HTML][HTML] Utilization of preimplantation genetic testing for monogenic disorders

I Lee, S Alur-Gupta, R Gallop, A Dokras - Fertility and sterility, 2020 - Elsevier
Objective To determine the rate of utilization, factors influencing the decision-making
process, and patient satisfaction with preimplantation genetic diagnosis for monogenic …

Perspectives of preimplantation genetic testing patients in Belgium on the ethics of polygenic embryo screening

M Siermann, JR Vermeesch, T Raivio, A Vanhie… - Reproductive …, 2024 - Elsevier
Research question What are the perspectives of preimplantation genetic testing (PGT)
patients in Belgium on the ethics of PGT for polygenic risk scoring (PGT-P)? Design In-depth …

A systematic review of the views of healthcare professionals on the scope of preimplantation genetic testing

M Siermann, Z Claesen, L Pasquier, T Raivio… - Journal of Community …, 2022 - Springer
Preimplantation genetic testing (PGT) involves testing embryos created through in vitro
fertilization for the presence of hereditary genetic disorders and chromosome abnormalities …

[HTML][HTML] How do patient perceived determinants influence the decision-making process to accept or decline preimplantation genetic screening?

MB Gebhart, RS Hines, A Penman, AC Holland - Fertility and Sterility, 2016 - Elsevier
Objective Identify the determinants that influence the patient's decision-making process
when deciding to accept or decline preimplantation genetic screening (PGS) in a given IVF …

Predictive genetic testing for amyotrophic lateral sclerosis and frontotemporal dementia: genetic counselling considerations

A Crook, K Williams, L Adams, I Blair… - … Lateral Sclerosis and …, 2017 - Taylor & Francis
Once a gene mutation that is causal of amyotrophic lateral sclerosis (ALS) and/or
frontotemporal dementia (FTD) is identified in a family, relatives may decide to undergo …

Mixed method systematic review: the relationship between breast cancer risk perception and health‐protective behaviour in women with family history of breast cancer

K Paalosalo‐Harris, H Skirton - Journal of advanced nursing, 2017 - Wiley Online Library
Aim The aim of this study was to determine and explore the relationship between risk
perception and health‐protective behaviour in individuals with family history of breast …