Bone mass is a key determinant of osteoporosis and fragility fractures. Epidemiologic
studies have shown that a 10% increase in peak bone mass (PBM) at the population level …

Peak bone mass (PBM) is a key determinant of bone mass and fragility fractures later in life.
The increase in bone mass during childhood and adolescence is mainly related to an …

With ageing, bone tissue undergoes significant compositional, architectural and metabolic
alterations potentially leading to osteoporosis. Osteoporosis is the most prevalent bone …

Bone remodeling is a lifelong process, due to the balanced activity of the osteoblasts (OBs),
the bone-forming cells, and osteoclasts (OCs), the bone-resorbing cells. This equilibrium is …

Background Many jumping interventions have been performed in children and adolescents
in order to improve bone-related variables and thus, ensure a healthy bone development …

Bone is a biomechanical tissue shaped by forces from muscles and gravitation.
Simultaneous bone and muscle decay and dysfunction (osteosarcopenia or sarco …

Background Periods of growth are thought to be the best time to increase bone mineral
content, bone area, and areal bone mineral density (aBMD) through increased loading …

Background: In the last decades, children's and adolescents' obesity and overweight have
increased in European Countries. Unhealthy eating habits and sedentary lifestyle have …

Peripubertal boys with autism spectrum disorder (ASD) have lower bone mineral density
(BMD) than typically developing controls. However, it is not clear whether lower BMD in ASD …

The purpose of this narrative review was to investigate the key determinants of
musculoskeletal health in childhood and adolescence, with particular attention to the role of …