Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds

M Amiri, O Molavi, S Sabetkam, S Jafari… - Cancer Cell …, 2023 - Springer
A growing body of evidence indicates that the anticancer effect of the immune system can be
activated by the immunogenic modulation of dying cancer cells. Cancer cell death, as a …

Green-synthesized silver nanoparticles from peel extract of pumpkin as a potent radiosensitizer against triple-negative breast cancer (TNBC)

S Montazersaheb, A Eftekhari, A Shafaroodi… - Cancer …, 2024 - Springer
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast
cancer. Radiation therapy (RT) is a modality for TNBC management. Radiosensitizers can …

Codelivery of metformin and methotrexate with optimized chitosan nanoparticles for synergistic triple-negative breast cancer therapy in vivo

A Karimian-Shaddel, H Dadashi, M Mashinchian… - International Journal of …, 2024 - Elsevier
The development of effective therapeutic strategies for triple-negative breast cancer (TNBC),
an aggressive subtype with limited treatment options, remains a critical challenge. This study …

[HTML][HTML] Silybin-functionalized PCL electrospun fibrous membranes for potential pharmaceutical and biomedical applications

C Spartali, AMG Psarra, SI Marras, C Tsioptsias… - Polymers, 2024 - mdpi.com
Silybin is a natural flavonolignan with potential anticancer, antioxidant, and hepatoprotective
properties. In the present study, various loadings of silybin (1, 3, and 5 wt%) were …

Chrysin and chrysin-loaded nanocarriers induced immunogenic cell death on B16 melanoma cells

Y Oliyapour, S Dabiri, O Molavi, MS Hejazi, S Davaran… - Medical Oncology, 2023 - Springer
Induction of immunogenic cell death (ICD) is a promising strategy for cancer
immunotherapy. Chrysin, which has potential anticancer effects, faces limitations in clinical …

Chitosan nanoparticles loaded with metformin and digoxin synergistically inhibit MCF-7 breast cancer cells through suppression of NOTCH-1 and HIF-1α gene …

H Dadashi, M Mashinchian, A Karimian-Shaddel… - International Journal of …, 2025 - Elsevier
This study investigated the potential anticancer efficacy of co-treating the MCF-7 breast
cancer cell line with chitosan nanoparticles (Cs NPs) loaded with metformin (Met) and …