The comprehensive landscape of miR-34a in cancer research

S Li, X Wei, J He, Q Cao, D Du, X Zhan, Y Zeng… - Cancer and Metastasis …, 2021 - Springer
Abstract MicroRNA-34 (miR-34) plays central roles in human diseases, especially cancers.
Inactivation of miR-34 is detected in cancer cell lines and tumor tissues versus normal …

Antitumor function of microRNA-122 against hepatocellular carcinoma

K Nakao, H Miyaaki, T Ichikawa - Journal of gastroenterology, 2014 - Springer
Abstract MicroRNA-122 (miR-122), a highly abundant and liver-specific miRNA, acts as a
tumor suppressor against hepatocellular carcinoma (HCC). Decreased expression of miR …

Circulating microRNAs in patients with chronic hepatitis C and non-alcoholic fatty liver disease

S Cermelli, A Ruggieri, JA Marrero, GN Ioannou… - PloS one, 2011 - journals.plos.org
MicroRNAs miR-122, miR-34a, miR-16 and miR-21 are commonly deregulated in liver
fibrosis and hepatocellular carcinoma. This study examined whether circulating levels of …

Circulating microRNAs as potential diagnostic and prognostic biomarkers in hepatocellular carcinoma

Y Jin, YS Wong, BKP Goh, CY Chan, PC Cheow… - Scientific Reports, 2019 - nature.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer with high mortality, due to
late diagnosis and limited treatment options. Blood miRNAs, which circulate in a highly …

MiR-122 in hepatic function and liver diseases

J Hu, Y Xu, J Hao, S Wang, C Li, S Meng - Protein & cell, 2012 - Springer
As the most abundant liver-specific microRNA, microRNA-122 (miR-122) is involved in
various physiological processes in hepatic function as well as in liver pathology. There is …

Serum microRNA signatures identified by Solexa sequencing predict sepsis patients' mortality: a prospective observational study

H Wang, P Zhang, W Chen, D Feng, Y Jia, L Xie - PloS one, 2012 - journals.plos.org
Background Sepsis is the leading cause of death in Intensive Care Units. Novel sepsis
biomarkers and targets for treatment are needed to improve mortality from sepsis …

Ectopic expression of microRNA-155 enhances innate antiviral immunity against HBV infection in human hepatoma cells

C Su, Z Hou, C Zhang, Z Tian, J Zhang - Virology journal, 2011 - Springer
Background Host innate antiviral immunity is the first line of defense against viral infection,
and is precisely regulated by thousands of genes at various stages, including microRNAs …

Hepatitis B virus mRNA-mediated miR-122 inhibition upregulates PTTG1-binding protein, which promotes hepatocellular carcinoma tumor growth and cell invasion

C Li, Y Wang, S Wang, B Wu, J Hao, H Fan… - Journal of …, 2013 - Am Soc Microbiol
As the most abundant liver-specific microRNA, miR-122 is involved in diverse aspects of
hepatic function and neoplastic transformation. Our previous study showed that miR-122 …

[HTML][HTML] Epigenetic regulation of miR-34a expression in alcoholic liver injury

F Meng, SS Glaser, H Francis, F Yang, Y Han… - The American journal of …, 2012 - Elsevier
Epigenetic changes are associated with the regulation of transcription of key cell regulatory
genes [micro RNAs (miRNAs)] during different types of liver injury. This study evaluated the …

Small noncoding RNAs in cells transformed by human T-cell leukemia virus type 1: a role for a tRNA fragment as a primer for reverse transcriptase

K Ruggero, A Guffanti, A Corradin, VK Sharma… - Journal of …, 2014 - Am Soc Microbiol
The present study employed mass sequencing of small RNA libraries to identify the
repertoire of small noncoding RNAs expressed in normal CD4+ T cells compared to cells …