The last international guidelines on the evaluation and management of primary
hyperparathyroidism (PHPT) were published in 2014. Research since that time has led to …

Primary hyperparathyroidism is a common endocrine disorder of calcium metabolism
characterised by hypercalcaemia and elevated or inappropriately normal concentrations of …

Highlights•Parathyroid hormone has dual anabolic and catabolic actions on the
skeleton.•The OPG–RANKL–RANK pathway is the main mediator of the catabolic actions of …

Objective: This report summarizes data on traditional and nontraditional manifestations of
primary hyperparathyroidism (PHPT) that have been published since the last International …

Primary hyperparathyroidism (PHPT) is a common disorder in which parathyroid hormone
(PTH) is excessively secreted from one or more of the four parathyroid glands. A single …

Primary hyperparathyroidism (PHPT), the most common cause of hypercalcemia, is most
often identified in postmenopausal women with hypercalcemia and parathyroid hormone …

High-resolution peripheral computed tomography (HR-pQCT) was developed to image bone
microarchitecture in vivo at peripheral skeletal sites. Since the introduction of HR-pQCT in …

Background The role of bone structure, one component of bone quality, has emerged as a
contributor to bone strength. The application of high-resolution imaging in evaluating bone …

Background Primary hyperparathyroidism (PHPT), the most common cause of
hypercalcemia, is most often identified in postmenopausal women. The clinical presentation …

PTH, an 84-amino acid peptide hormone synthesized by the parathyroid glands, is essential
for the maintenance of calcium homeostasis. While in its traditional metabolic role, PTH …