Roles of microRNAs in mammalian reproduction: from the commitment of germ cells to peri‐implantation embryos

AMMT Reza, YJ Choi, SG Han, H Song… - Biological …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are active regulators of numerous biological and physiological
processes including most of the events of mammalian reproduction. Understanding the …

[HTML][HTML] The molecular regulation in the pathophysiology in ovarian aging

CJ Li, LT Lin, HW Tsai, CU Chern, ZH Wen… - Aging and …, 2021 - ncbi.nlm.nih.gov
The female reproductive system is of great significance to women's health. Aging of the
female reproductive system occurs approximately 10 years prior to the natural age …

MicroRNAs: tiny molecules with a significant role in mammalian follicular and oocyte development

D Tesfaye, S Gebremedhn, D Salilew-Wondim… - …, 2018 - rep.bioscientifica.com
The genetic regulation of female fertility (follicular development, oocyte maturation and early
preimplantation embryo development) involves the spatio-temporal regulation of those …

The expression of miRNAs in human ovaries, oocytes, extracellular vesicles, and early embryos: a systematic review

A Salas-Huetos, ER James, KI Aston, TG Jenkins… - Cells, 2019 - mdpi.com
The recent discovery of microRNAs (miRNAs) in human reproductive tissues and cells
indicates a possible functional role in reproductive function. However, the studies published …

[HTML][HTML] MicroRNAs in combined spent culture media and sperm are associated with embryo quality and pregnancy outcome

M Abu-Halima, ZA Khaizaran, BM Ayesh, U Fischer… - Fertility and sterility, 2020 - Elsevier
Objective To identify differentially abundant miRNAs in sperm samples and spent culture
media (SCM) of embryos of different grade toward a prediction of pregnancy outcome …

MicroRNA-21 enhances estradiol production by inhibiting WT1 expression in granulosa cells

RE Hilker, B Pan, X Zhan, J Li - Journal of Molecular …, 2022 - jme.bioscientifica.com
In antral follicles, transition of proliferative granulosa cells to estradiol-producing is critical for
proper oocyte maturation. MicroRNAs are noncoding RNAs that play important roles in …

STAT3 signaling stimulates miR-21 expression in bovine cumulus cells during in vitro oocyte maturation

A Tscherner, AC Brown, L Stalker, J Kao, I Dufort… - Scientific reports, 2018 - nature.com
MicroRNAs are potent regulators of gene expression that have been widely implicated in
reproduction and embryo development. Recent studies have demonstrated that miR-21, a …

BPA decreases PDCD4 in bovine granulosa cells independently of miR-21 inhibition

R Sabry, M Williams, N Werry, J LaMarre… - International Journal of …, 2022 - mdpi.com
microRNAs (miRNAs) are susceptible to environmental factors that might affect cellular
function and impose negative effects on female reproduction. miR-21 is the most abundant …

Impact of the number of retrieved oocytes on IVF outcomes: oocyte maturation, fertilization, embryo quality and implantation rate

M Jamil, H Debbarh, A Kabit, M Ennaji, M Zarqaoui… - Zygote, 2023 - cambridge.org
The process of oocyte retrieval represents a key phase during the cycles of in vitro
fertilization (IVF). It involves controlled ovarian stimulation to retrieve the highest number of …

[HTML][HTML] miR-142-3p as a biomarker of blastocyst implantation failure-A pilot study

E Borges Jr, AS Setti, DPAF Braga… - JBRA assisted …, 2016 - ncbi.nlm.nih.gov
Objective This study aims to find whether microRNAs (miRNAs) detected in the culture
medium of embryos produced in vitro could be potential biomarkers of embryo implantation …