Advanced therapies combating acute and chronic skin wounds are likely to be brought
about using our knowledge of regenerative medicine coupled with appropriately tissue …

Entity or Function? specific adult stem cell may need to be expanded. Accordingly, adult
stem cells may not only act locally in the tissues in which they reside, but may also be …

Some proclaim that the major principles of development tors such as hormones, however,
influence final organ are now understood (Wolpert, 1996). Yet one of the most size. Growth …

In this review we compile and discuss the published plethora of cell biological effects which
are ascribed to electric fields (EF), magnetic fields (MF) and electromagnetic fields (EMF). In …

A major issue in regenerative medicine is the role of injury in promoting cell plasticity. Here
we explore the function of reactive oxygen species (ROS) induced through lesions in adult …

Do tumours arise from stem cells, or are they derived from more differentiated cells that, for
some reason, begin to recapitulate developmental programmes? Inappropriate activation of …

The limb blastemal cells of an adult salamander regenerate the structures distal to the level
of amputation, and the surface protein Prod 1 is a critical determinant of their proximodistal …

Transforming growth factor-β1 (TGF-β1) is thought to play a crucial role in fibrotic diseases.
This study demonstrates for the first time that TGF-β1 stimulation can induce myoblasts …

Many organisms have the ability to shed an appendage (autotomy) to escape a predator or
fouled molting event. Despite its immediate advantage on survivorship, autotomy can have …

Post-embryonic neurogenesis is a fundamental feature of the vertebrate brain. However, the
level of adult neurogenesis decreases significantly with phylogeny. In the first part of this …