Flaviviruses are small enveloped virions that enter target cells in a pH-dependent fashion.
Virus attachment, entry, and membrane fusion are orchestrated by the envelope (E) and pre …

West Nile virus (WNV) is a neurotropic ffavivirus that has emerged globally as a significant
cause of viral encephalitis. WNV is maintained in an enzootic cycle between mosquitoes …

Antibody binding to the icosahedral arrangement of envelope proteins on the surface of
flaviviruses can result in neutralization or enhancement of infection. We evaluated how …

Dengue viruses (DENV) are the etiological agents of dengue fever (DF) and dengue
hemorrhagic fever (DHF). The DENV complex consists of four closely related viruses …

Background. Infection with any 1 of the 4 dengue viruses (DVs) can produce several
illnesses, ranging from a mild febrile illness to classic dengue fever (DF) to dengue …

Flaviviruses are group of single stranded RNA viruses that cause severe endemic infection
and epidemics on a global scale. It presents a significant health impact worldwide and the …

Neutralization of flaviviruses in vivo correlates with the development of an antibody
response against the viral envelope (E) protein. Previous studies demonstrated that …

Antibody-dependent enhancement (ADE) has been proposed as a mechanism to explain
dengue hemorrhagic fever (DHF) in the course of a secondary dengue infection. Very …

Dengue is a mosquito-borne disease which causes significant public health concerns in
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …

Flaviviruses are a group of~ 70 small RNA viruses responsible for significant morbidity and
mortality across the globe. Efforts to develop effective vaccines for several clinically …