Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …

Mesenchymal stem cell-derived exosomes (MSC-Exos) have been utilized as medicinal
agents or as delivery vehicles in cartilage injuries and cartilage-based diseases. Given the …

BACKGROUND Osteoarthritis (OA) is the most common joint disorder, is associated with an
increasing socioeconomic impact owing to the ageing population. AIM To analyze and …

Stem cells can be defined as the cells that have the capacity to both self-renew and give rise
to differentiated cells. Under the right conditions and signals, depending on their origin and …

Cellular therapy offers regeneration which curbs osteoarthritis of the knee. Among cellular
therapies, mesenchymal stromal cells (MSCs) are readily isolated from various sources as …

Introduction Regenerative therapy has shown promising results in the treatment of
osteoarthritis (OA) knee with Kellgren–Lawrence (KL) Grades I–III. We compared the safety …

Mesenchymal stromal cells (MSCs) are cells with the characteristic ability of self-renewal
along with the ability to exhibit multilineage differentiation. Bone marrow (BM) is the first …

Purpose The aim of this systematic review was to determine if adipose tissue-derived cell-
based injectable therapies can induce disease-modifying effects in joints affected by …

Tissue engineering and regenerative medicine (TERM) have paved a way for treating
musculoskeletal diseases in a minimally invasive manner. The regenerative medicine …

The effects of differentiated cells on stem cell differentiation were analyzed via co-culturing
using a cell-encapsulated double-layered hydrogel system. As a polymer hydrogel matrix, a …