Matrix metalloproteinases (MMPs) are a large family of zinc-endopeptidases which play
important roles in multiple physiological and pathological processes. These enzymes are …

Background Ischemic stroke (IS) is a complex and devastating vascular disease that has
become one of the leading causes of disability and mortality worldwide. Several studies …

Context: Matrix metalloproteinases are involved in atherosclerosis and plaque vulnerability.
Objective: To investigate serum levels and genetic polymorphisms of matrix …

Atherosclerosis is a complex multifocal arterial disease involving interactions of multiple
genetic and environmental factors. Advances in techniques of molecular genetics have …

Atherosclerosis is now widely recognized as a chronic inflammatory disease that involves
innate and adaptive immune responses. Both cellular and humoral components of the …

Interactions of cell with the extracellular matrix (ECM) are crucial for normal development
and functioning of the human organism. By regulating ECM integrity and composition matrix …

Carotid atherosclerosis (CAS) is associated with increased cardiovascular risk, and
therefore, assessing the genetic versus environmental background of CAS traits is of key …

The family of matrix metalloproteinases (MMPs) comprises 24 multidomain enzymes with a
zinc-dependent activity. Their structural diversity over the archetypal domain organization …

Background Myocardial infarction (MI) leads to ischemia and afterward to left ventricular (LV)
remodeling. Matrix metalloproteinase− 1 (MMP1) and− 3 (MMP3) belong to the family of …

Introduction and hypothesis To investigate the associations between single nucleotide
polymorphism (SNP) type 1G/2G at position− 1607/− 1608 of the matrix metalloproteinase …