This review explores the interface between circadian timekeeping and the regulation of
brain function by astrocytes. Although astrocytes regulate neuronal activity across many time …

Circadian clocks participate in the coordination of various metabolic and biological activities
to maintain homeostasis. Disturbances in the circadian rhythm and cancers are closely …

Background and purpose: Radioresistance remains a significant challenge in tumor therapy.
This systematic review aims to demonstrate the role of long non-coding RNA (lncRNA) in …

Radiotherapy is the cornerstone of treatment of high-grade gliomas (HGGs). It eradicates
tumor cells by inducing oxidative stress and subsequent DNA damage. Unfortunately …

Post-traumatic osteoarthritis is a prevalent debilitating joint disease. However, there is no
FDA-approved disease-modifying osteoarthritis drug currently. Gene therapy can improve …

Gliomas are the most common primary intracranial tumors and closely related to circadian
clock. Due to the high mortality and morbidity of gliomas, exploring novel diagnostic and …

Abstract Nuclear transcription factor Mesenchyme Homeobox 2 (MEOX2) is a homeobox
gene that is originally discovered to suppress the growth of vascular smooth muscle and …

Glioblastoma (GBM) is the most prevalent malignant primary brain tumor, accounting for
14.2% of all diagnosed tumors and 50.1% of all malignant tumors, and the median survival …

Background Micro-ribonucleic acids (miRNAs) are involved in osteoarthritis (OA)
pathogenesis and clock-controlled genes (CCGs) regulation. However, the interaction …

Hormone therapy resistance and the ensuing aggressive tumor progression present a
significant clinical challenge. However, the mechanisms underlying the induction of tumor …