Thyroid hormone: sex-dependent role in nervous system regulation and disease

S Baksi, A Pradhan - Biology of sex differences, 2021 - Springer
Thyroid hormone (TH) regulates many functions including metabolism, cell differentiation,
and nervous system development. Alteration of thyroid hormone level in the body can lead …

Primary hypothyroidism and Alzheimer's Disease: a tale of two

FH AlAnazi, HM Al-Kuraishy, A Alexiou… - Cellular and Molecular …, 2023 - Springer
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …

Cognitive dysfunction: a growing link between diabetes and Alzheimer's disease

K Jash, P Gondaliya, P Kirave… - Drug development …, 2020 - Wiley Online Library
Diabetes mellitus (DM) is a gradually rising metabolic disease which is currently affecting
millions of people worldwide. Diabetes is associated with various complications like …

[HTML][HTML] The role of thyroid dysfunction in Alzheimer's disease: a systematic review and meta-analysis

A Salehipour, M Dolatshahi, M Haghshomar - The journal of prevention of …, 2023 - Elsevier
Imbalances in thyroid hormones have been linked with Alzheimer's dementia. Several
studies have reported an association between thyroid disorders, such as hyper-or …

[HTML][HTML] Cadmium-promoted thyroid hormones disruption mediates ROS, inflammation, Aβ and Tau proteins production, gliosis, spongiosis and neurodegeneration in …

E Sola, P Moyano, A Flores, JM García, J García… - Chemico-Biological …, 2023 - Elsevier
Cadmium (Cd) produces cognition decline following single and repeated treatment,
although the complete mechanisms are still unrevealed. Basal forebrain (BF) cholinergic …

[HTML][HTML] The role of thyroid-stimulating hormone in regulating lipid metabolism: Implications for body–brain communication

X Wang, Z Wu, Y Liu, C Wu, J Jiang, K Hashimoto… - Neurobiology of …, 2024 - Elsevier
Thyroid-stimulating hormone (TSH) is a pituitary hormone that stimulates the thyroid gland to
produce and release thyroid hormones, primarily thyroxine and triiodothyronine. These …

Hypothyroidism and cognitive disorders during development and adulthood: implications in the central nervous system

P Salazar, P Cisternas, M Martinez… - Molecular …, 2019 - Springer
Thyroid hormones (THs) play a critical function in fundamental signaling of the body
regulating process such as metabolism of glucose and lipids, cell maturation and …

Metabolic determinants of Alzheimer's disease: A focus on thermoregulation

M Tournissac, M Leclerc, J Valentin-Escalera… - Ageing Research …, 2021 - Elsevier
Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …

Hypothyroidism and diabetes-related dementia: Focused on neuronal dysfunction, insulin resistance, and dyslipidemia

HK Kim, J Song - International Journal of Molecular Sciences, 2022 - mdpi.com
The incidence of dementia is steadily increasing worldwide. The risk factors for dementia are
diverse, and include genetic background, environmental factors, sex differences, and …

Association between thyroid function and Alzheimer's disease: A systematic review

PBS Figueroa, AFF Ferreira, LR Britto… - Metabolic Brain …, 2021 - Springer
Alterations in metabolic parameters have been associated with an increased risk of
dementia, among which thyroid function has gained great importance in Alzheimer's disease …