The number of molecularly stratified treatment options available to patients with colorectal
cancer (CRC) is increasing, with a parallel rise in the use of biomarkers to guide …

Lung cancer is the leading cause of death for malignancy worldwide. Its molecular profiling
has enriched our understanding of cancer initiation and progression and has become …

The association between mutations of key driver genes and colorectal cancer (CRC)
metastasis has been investigated by many studies. However, the results of these studies …

Purpose A systematic literature review was conducted to estimate the global prevalence of
Kirsten rat sarcoma virus gene (KRAS) mutations, with an emphasis on the clinically …

Cholangiocarcinoma (CCA) is a highly-aggressive malignancy arising from the biliary tree,
characterized by a steady increase in incidence globally and a high mortality rate. Most …

RAS oncogene affects numerous cellular functions including growth, proliferation, apoptosis,
migration, division and differentiation of the cells. It has 3 known isoforms as Harvey-RAS …

Background Colorectal cancer is the third most common cancer in the world. In this study,
we assessed the long-term survival characteristics and prognostic associations and …

Simple Summary Cholangiocarcinoma constitutes around 3% of gastrointestinal cancers,
and mortality from this cancer has been rising in the recent decades. Many cases of …

This study aimed to estimate the incidence of KRAS, NRAS, and BRAF mutations in the
Moroccan population, and investigate the associations of KRAS and NRAS gene mutations …

Introduction Multiple primary melanomas (MPM) occur up to 8% of patients with cutaneous
malignant melanoma (CMM). They are often sporadic harbouring several somatic mutations …