Hyperspectral retinal imaging in Alzheimer's disease and age-related macular degeneration: a review

X Du, J Park, R Zhao, RT Smith, Y Koronyo… - Acta Neuropathologica …, 2024 - Springer
While Alzheimer's disease and other neurodegenerative diseases have traditionally been
viewed as brain disorders, there is growing evidence indicating their manifestation in the …

[HTML][HTML] Non-Invasive Retinal Biomarkers for Early Diagnosis of Alzheimer's Disease

S Kaštelan, A Gverović Antunica, V Puzović… - Biomedicines, 2025 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain
associated with ageing and is the most prevalent form of dementia, affecting an estimated 55 …

pTau pathology in the retina of TAU58 mice: association with ganglion cell degeneration and implications on seeding and propagation of pTau from human brain …

G Walkiewicz, A Ronisz, S Ospitalieri, G Tsaka… - Acta Neuropathologica …, 2024 - Springer
The accumulation of abnormal phosphorylated Tau protein (pTau) in neurons of the brain is
a pathological hallmark of Alzheimer's disease (AD). PTau pathology also occurs in the …

[HTML][HTML] Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease

MR Davis, E Robinson, Y Koronyo… - …, 2024 - pmc.ncbi.nlm.nih.gov
Accumulation of pathological tau isoforms, especially hyperphosphorylated tau at serine 396
(pS396-tau) and tau oligomers, has been demonstrated in the retinas of patients with mild …

[HTML][HTML] Retinal structure and its relationship with premorbid, clinical, and cognitive variables in young Spanish patients with early course schizophrenia spectrum …

JM González-Díaz, BS Dalmau… - European …, 2025 - Elsevier
Emerging evidence suggests that retinal structural alterations are present in schizophrenia
spectrum disorders (SSD), potentially reflecting broader neurodevelopmental and …

Retinal and Optic Nerve Lesions Correspond to Amyloid in Autosomal Dominant Alzheimer's Disease

AH Kashani, M Koronyo-Hamaoui, Y Koronyo, H Shi… - medRxiv, 2025 - medrxiv.org
Autosomal dominant Alzheimer's disease (ADAD) is a rare form of Alzheimer's disease (AD)
in which the biology of the disease can be explored during the presymptomatic phase of the …

[HTML][HTML] Protein Citrullination in Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases

IO Yusuf, W Camille, PR Thompson… - Journal of experimental …, 2024 - pmc.ncbi.nlm.nih.gov
Protein citrullination (PC) is a posttranslational modification (PTM) that converts a peptidyl
arginine into a peptidyl citrulline. Aberrant PC is a hallmark of neurodegenerative diseases …

[PDF][PDF] Effects of Estradiol and other Selective Estrogen Receptor Modulators on Human Temporal Lobe Cortex Astroglial Cell Spreading

I Silva, FN Naftolin, A Williamson, A Fadiel, D Spencer… - 2024 - preprints.org
Rationale: Astroglial cells (astrocytes), previously considered mere support cells in the
central nervous system, are now understood to be key players in integrating neuronal inputs …