Metastasis causes death of 90% of cancer patients, so it is the most significant issue
associated with cancer disease. Thus, it is no surprise that many researchers are trying to …

E-cadherin is the core component of epithelial adherens junctions, essential for tissue
development, differentiation, and maintenance. It is also fundamental for tissue barrier …

Background: Loss of CDH1 (E-cadherin) expression in cancer cells may promote cell
migration and invasion. Therefore, we hypothesised that loss of CDH1 expression in …

Epithelial-mesenchymal transition (EMT) is a complex developmental program that enables
carcinoma cells to suppress their epithelial features changing to mesenchymal ones. This …

Aims Accumulating evidence over the past decade has shown that abnormal activation of
epithelial to mesenchymal transition (EMT) contributes to tumour progression and …

Background β-catenin plays a key role in the progression of colorectal cancer (CRC).
However, its prognostic significance for patients with CRC remains controversial …

Abstract β-catenin is a key component of Wnt signalling, which plays a crucial role in CRC
progression. Therefore, a meta-analysis was performed to assess the prognostic value of β …

The abnormal activation of the Wnt/β-catenin pathway frequently occurs in colorectal cancer.
The nuclear translocation of β-catenin activates the transcription of target genes that …

Purpose The effect of E-cadherin on colorectal cancer is still controversial. In order to clarify
the effect of E-cadherin on the prognosis and clinicopathological features of colorectal …

Nasopharyngeal carcinoma has a high incidence in southern China. The Wnt/β-catenin
signaling pathway plays a major role in cancer development and progression. Our current …